In the face of the unprecedented challenges posed by the COVID-19 pandemic, which has affected millions globally, N1-Methyl-Pseudouridine Triphosphate emerged as a key ingredient in the fight against the virus. As a critical RNA modification in the mRNA vaccines developed by Pfizer-BioNTech (Comirnaty®) and Moderna Therapeutics (Spikevax®), it has played a vital role in achieving efficacies surpassing 90%.
N1-Methyl-Pseudouridine Triphosphate represents a significant advancement in RNA-based therapeutics, offering a promising path forward not only in responding to pandemics but also in the broader field of vaccine research and development. Its impact on mRNA vaccine efficacy marks a turning point in medical science, showcasing the potential of innovative molecular approaches in combating global health crises.
- Chemical name: N¹-Methylpseudouridine 5′-Triphosphate Sodium Salt
- Molecular formula:C10H14N2Na3O15P3
- Molecular Weight: 564.11
- Cas NO.:1428903-59-6
- Grade: Injection, purity 99%
- Form: liquid
- Concentration: 100mM
Storage: -80°C, 6 months; -20°C, 1 month (protect from light)
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